![]() The enhancement of adhesiveness may be mediated by the increased synthesis of dolichol-linked oligosaccharides and also may be related to the increased synthesis of fibronectin. The results indicated that dibutyryl cyclic AMP increased the synthesis of dolichol-linked oligosaccharides and N-glycosylation of proteins in AH 70Btc cells. Synonym(s): Bucladesine sodium salt Dibutyryl cAMP sodium salt Dibutyryl cyclic-AMP sodium salt Empirical Formula: C 18 H 23 N 5 NaO 8 P Linear Formula: C 18 H 23 N 5 O 8 PNa Formula Weight: 491. Both the effects on the glycosylation pathway and on adhesiveness of cells were reversed by further treatment of the cells with 1 microgram of tunicamycin/ml. In addition to the above effects, dibutyryl cyclic AMP enhanced the adhesiveness of AH 70Btc cells to glass surfaces. Synonym(s): Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt. of 220 000 and 185 000 was shown to be linked to increased synthesis of the polypeptide portion. N 6,2-O-Dibutyryladenosine 3,5-cyclic monophosphate sodium salt. Increased glycosylation of the glycoproteins with mol.wts. of 220 000 and two other high-molecular-weight glycoproteins (apparent mol.wts. Analysis of cellular glycoproteins by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis after reduction showed that dibutyryl cyclic AMP specifically enhanced the glycosylation of a fibronectin-like glycoprotein with an apparent mol.wt. ![]() ![]() Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt. Adenosine 3,5-cyclic Monophosphate, N,O 2-Dibutyryl-. Substantial increases in both 3/3-OH sterol and fatty acid synthesis were observed after concanavalin A addition to mouse spleen lymphocytes cultured. ![]() Moreover, dibutyryl-cAMP treatment of differentiated NSC-34 cells caused intracellular ROS generation and cell death. These increases in caspase-3 protein expression were suppressed by pretreatment with NAC. At the same time, dibutyryl cyclic AMP increased the incorporation of glucosamine into dolichol-linked N-acetylglucosamine and NN′-diacetylchitobiose about 1.5-fold and into dolichol-linked oligosaccharides about 3-fold. Find dibutyryl camp and related products for scientific research at MilliporeSigma. Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Western blot analysis revealed that the active form of caspase-3 was markedly increased in the PGE2- and butaprost-treated cells. When the hepatoma cells (AH 70Btc, Clone 10-5) were cultured in the presence of 1 mM-dibutyryl cyclic AMP for 2 days, the incorporation of glucosamine into protein was increased over 2-fold. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |